Connexin 43/GJA1 anticorps

N° du produit ABIN641009

L’anticorps Lapin Polyclonal anti-Connexin 43/GJA1 a été validé pour WB, ELISA et Func. Il convient pour détecter Connexin 43/GJA1 dans des échantillons de Poulet.

Aperçu rapide pour Connexin 43/GJA1 anticorps (ABIN641009)

Antigène: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reactivité: Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Connexin 43/GJA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Functional Studies (Func)

Détail du produit anti-Connexin 43/GJA1 anticorps

Fonction: Rabbit Anti-Chicken Connexin 43 (pSer368)

Specificité: This product recognizes chicken Interferon gamma (chIFN-gamma). Original studies investigating the properties of chicken Interferon (chIFN), revealed properties similar to mammalian IFN type I (IFNI), and it has since become apparent that there are at least three distinct chicken interferon proteins, designated as chIFN-alpha, chIFN-beta and chIFN-gamma. chIFN-gamma was first identified, when supernatant from chicken spleen cells stimulated with concanavalin A (ConA ), displayed macrophage-activating factor (MAF) activity - the principle function of mammalian type II IFN-gamma. Several independent studies have since supported the existence of this chicken homolog, by the cloning of IFN-gamma cDNA from activated chicken T cells and demonstrating that recombinant chicken IFN-gamma strongly upregulates the expression of MHC class II and iNOS genes. It can be used to neutralize chIFN-gamma activity and to discriminate the antiviral activity of chIFN-gamma from that of chIFN-alpha and chIFN-beta (2).

Attributs du produit: Adhesion Molecule/Cell Surface

Immunogène: Antisera to chicken Interferon Gamma were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography on protein G.

Isotype: IgG

Information d'application

Indications d'application: ELISA, Functional Assays, Western Blotting

Restrictions: For Research Use only

Stockage

Concentration: IgG concentration 0.5 mg/ml

Buffer: Phosphate buffered saline

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur Connexin 43/GJA1

Antigène: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Autre désignation: Connexin 43

Pathways: Signalisation MAPK, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization